Pain medications work to relieve discomfort, but many serious concerns exist about the current available pain relief treatments. Addiction, overdose and side effects are all a part of the “Pain Problem”. In this episode of Research Detectives, we introduce viewers to the scientists who are working to solve this problem through a better understanding of the science of pain and how our body sends pain signals. We’ll also meet researchers who study drug cravings and tolerance to see if it’s possible to make pain medicines that don’t require increased doses to remain effective.